ncRNA name | Cx43 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | retinas |
Methods | siRNA injection, Western blot, immunostaining, TUNEL assay |
Expression pattern | associated |
Functional description | The number of apoptotic cells, ACs and PL, FITC-dex extravasation, and thickness increased in the retinas of the diabetic and Cx43 siRNA-treated rats compared to those of the control rats. |
PubMed ID | 24940027 |
Year | 2014 |
Title | Downregulation of Connexin 43 promotes vascular cell loss and excess permeability associated with the development of vascular lesions in the diabetic retina. |
Drug-related ncRNA | NO |
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