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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name Cx43 siRNA
ncRNA Category siRNA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line retinas
Methods siRNA injection, Western blot, immunostaining, TUNEL assay
Expression pattern associated
Functional description The number of apoptotic cells, ACs and PL, FITC-dex extravasation, and thickness increased in the retinas of the diabetic and Cx43 siRNA-treated rats compared to those of the control rats.
PubMed ID 24940027
Year 2014
Title Downregulation of Connexin 43 promotes vascular cell loss and excess permeability associated with the development of vascular lesions in the diabetic retina.
Drug-related ncRNA NO

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